It belongs to the class of medicines known as tetracycline antibiotics
Sarecycline is a novel, tetracycline-class antibiotic specifically designed to treat inflammatory acne
It belongs to the class of medicines known as tetracycline antibiotics
Sarecycline is an oral, once daily, narrow spectrum tetracycline used to treat moderate-to-severe acne
Sarecycline is a tetracycline-derived oral antibiotic, specifically designed for acne, and is approved by the Food and Drug Administration (FDA) in 2018 for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris (AV) in patients 9 years of age and older
Sarecycline is a ribosomal protein inhibitor of the tetracycline class that displays potent activity against P
It is available only in an oral formulation and approved for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 9 years old and older [56]
1, 8
The original base medicines, chlortetracycline, tetracycline, and oxytetracycline, have been replaced by products that are better absorbed and more lipophilic, with excellent tissue distribution
However, this medicine is not used to prevent or treat infections
(8
Linda Stein Gold, MD: Doxycycline was FDA approved in 1967 and minocycline has been used for more than 30 years, so it has been quite a long time since we have had a new oral antibiotic for acne
Tetracyclines are a group of antibiotics whose first representative was discovered over 70 years ago
21 In a nonclinical study, sarecycline showed limited activity against enteric Gram-negative bacteria, yet potent
Sarecycline is a tetracycline class antibiotic with a narrow spectrum of activity targeting P acnes and Staphylococcus aureus and more limited activity against gram-negative gastrointestinal organisms than minocycline and doxycycline
The aim of this article was to evaluate the data from published clinical trials of sarecycline in the treatment of acne, review the drug's pharmacology, and understand how this new medication may apply to clinical practice